The INSPIRE bio resource platform relies on several research devices called research cohorts. The word cohort is a synonym for group of individuals, which is mainly used in research (medical, demographic, sociological, etc.).
This platform extends its research from animal to human, from cell to individual and from basic research to clinical application, which is why it is defined as translational research.
The main human cohort will consist of a group of 1,000 volunteers (currently being recruited), aged 20 to over 100 years. Through these participants, the INSPIRE-T cohort will bring together many biological, tissue, clinical, imaging and digital resources needed by the different research teams for translational research programs in humans, in comparison with what is studied on animal models. Discover the INSPIRE human translational research cohort and pre-existing cohorts
For translational research, the INSPIRE platform is based on several animal cohorts (or models). The INSPIRE animal cohort includes 1,400 mice, and is one of the 3 largest animal cohorts on aging in the world with the National Institute on Aging (Baltimore, USA) and Calico (Google in California, US). Research on this animal cohort will be complemented by a specific fish model, the Nothobranchius furzeri or African Killifish, whose ageing model is particularly interesting. Finally, a canine cohort, in real life conditions, should be set up soon. Discover the animal cohorts INSPIRE
Two other human cohorts exist and are focused on primary care & prevention to avoid the loss of autonomy among senior people by implementing the WHO ICOPE program (Integrated Care for Older People). They are the ICOPE CARE cohort and the digital cohort. Know more.